Vaccines: Pubs/SurvManual/main page

Manual for the Surveillance of Vaccine-Preventable Diseases
4th Edition, 2008

The Manual for the Surveillance of Vaccine-Preventable Diseases provides current guidelines for those directly involved in surveillance of vaccine-preventable diseases, especially personnel at the local health departments. For each of the vaccine-preventable diseases, this manual includes a chapter describing the importance of rapid case identification; the importance of surveillance; disease reduction goals; case definitions (including clinical description and case classifications); epidemiologically important data to be collected during case investigation; activities for enhancing surveillance; activities for case investigation; and activities for outbreak control. Other chapters include information on surveillance indicators; surveillance data analyses; reporting adverse events following vaccination; and enhancing surveillance. In addition, the manual includes a section reserved for insertion of state-specific guidance for VPD surveillance and extensive appendices.


On This Page:

Compressed Section Bundles
Individual Downloads
List of Chapters
List of Appendices updated

This manual is available only through this website and is no longer offered in a printed version. Offering the manual online keeps the manual as current as possible. As changes occur, the chapters will be replaced with updated versions.

Compressed Section Bundles
These compressed bundles, saved in .zip format, contain all the files for each section (outlined below) and may have a file size prohibitive to those with slow Internet connections.

All Front Matter (PDF 269 KB)
All Chapters (PDF 3.43 MB)
WARNING: file size is large and will take a while to download.




Individual Downloads
The individual files of the 2008 Manual for the Surveillance of Vaccine-Preventable Diseases are listed below and were initially posted August 2008.

List of Front Matter
Front portion of manual (PDF 269 KB)
Cover, spine, title pages (titles and acknowledgements), acronyms, definition of terms, table of contents, introduction, etc.


List of Chapters
The first link goes directly to the chapter's web page. However, most will want to print these chapters using the second link (PDF) which opens in Adobe Reader.

Chapter 1: Diphtheria ( PDF 359 KB)
Chapter 2: Haemophilus influenzae type b ( PDF 366 KB)
Chapter 3: Hepatitis A ( PDF 321 KB)
Chapter 4: Hepatitis B ( PDF 413 KB)
Chapter 5: Human Papillomavirus ( PDF 366 KB)
Chapter 6: Influenza ( PDF 283 KB) updated Apr 8, 2009
Chapter 7: Measles ( PDF 531 KB) updated Apr 8, 2009
Chapter 8: Meningococcal ( PDF 350 KB)
Chapter 9: Mumps ( PDF 427 KB) updated Apr 8, 2009
Note: Guidance related to the duration of time that mumps patients should be isolated following onset of symptoms has changed. Consult the MMWR: Updated Recommendations for Isolation of Persons with Mumps. This MMWR supersedes the outdated information found in Chapter 9: Mumps in Section XIII - Outbreak Control. (Oct 2008)

Chapter 10: Pertussis ( PDF 458 KB)
Chapter 11: Pneumococcal ( PDF 431 KB)
Chapter 12: Polio ( PDF 97 KB) Note: This chapter is not yet available.
Meanwhile, please consult last edition's Polio Chapter.
Chapter 13: Rotavirus ( PDF 430 KB)
Chapter 14: Rubella ( PDF 434 KB)
Chapter 15: Congenital Rubella Syndrome ( PDF 366 KB)
Chapter 16: Tetanus ( PDF 407 KB)
Chapter 17: Varicella ( PDF 508 KB)
Chapter 18: Surveillance Indicators ( PDF 324 KB)
Chapter 19: Enhancing Surveillance ( PDF 292 KB)
Chapter 20: Analysis of Surveillance Data ( PDF 357 KB)
Chapter 21: Surveillance for Adverse Events Following Vaccination ( PDF 417 KB)
Chapter 22: Laboratory Support for the Surveillance of Vaccine-Preventable Diseases ( PDF 749 KB)
Chapter 23: National Surveillance of Vaccine-Preventable Diseases ( PDF 294 KB)
Chapter 24: State-Specific Surveillance of Vaccine-Preventable Diseases ( PDF 140 KB)


List of Appendices
Below is a list of appendices for the Manual of Surveillance of Vaccine-Preventable Diseases. As they are completed, a link will be provided to the appendix. Please check back often. If you wish to be notified by email when this web page is updated and hence when appendices are added, please use the Get Email Updates link located at the top of this page.

Appendix 1: Collection of Specimens for Isolation of C. diphtheriae (Ch. 1) (168 KB, 1 page) Dec 5, 2008 removed temporarily for corrections

Appendix 2: Guidelines for managing a suspected case of diphtheria and for managing contacts (Ch. 1) (433 KB, 10 pages) Dec 5, 2008
removed temporarily for corrections

Appendix 3: CDC Diphtheria Worksheet (Ch. 1)

Appendix 4: Haemophilus influenzae Surveillance Worksheet (Ch. 2)
removed temporarily for corrections
– (Abbreviated Worksheet Option) (69 KB, 1 page) Jan 8, 2009
– (Expanded Worksheet Option) (433 KB, 3 pages) Jan 8, 2009

Appendix 5: Haemophilus influenzae type b Vaccine and Extended Information Worksheet (Ch. 2) (103 KB, 2 pages) Jan 20, 2009
removed temporarily for corrections

Appendix 6: Hepatitis Data Collection Worksheet (Ch. 3 and 4) (807 KB, 6 pages) Feb 23, 2009

Appendix 7: Measles Virus Isolation Instructions (Ch. 7) (298 KB, 4 pages) Jan 20, 2009

Appendix 8: Measles Surveillance Worksheet (Ch. 7)
- (Instructions) (166 KB, 2 pages) Jan 8, 2009
- (Worksheet) (385 KB, 2 pages) Jan 8, 2009
Appendix 9: Meningococcal Disease Surveillance Worksheet (Ch. 8)
– Version 1 (formerly NETSS)
- Version 2 (formerly NEDSS)

Appendix 10: Mumps Surveillance Worksheet (Ch. 9)
- (Instructions) (166 KB, 2 pages) Mar 18, 2009
- (Worksheet) (373 KB, 2 pages) Mar 18, 2009

Appendix 11: Pertussis Surveillance Worksheet (Ch. 10)
– (Instructions) (195 KB, 3 pages) Updated Aug 7, 2009
- (Worksheet) (83 KB, 2 pages) Updated Aug 7, 2009

Appendix 12: Pertussis Death Worksheet (Ch. 10) (99 KB, 4 pages) Jan 20, 2009
removed - Pertussis Death Worksheet is no longer in use.

Appendix 13: Streptococcus pneumoniae Surveillance Worksheet (Ch. 11) (85 KB, 2 pages) Feb 10, 2009

Appendix 14: Suspected Polio Case worksheet Investigation of suspected case of poliomyelitis (Ch. 12)

Appendix 15: Collection of Specimens for Typing of Rubella Virus (Ch. 14) (204 KB, 2 pages) Jan 20, 2009

Appendix 16: Rubella Surveillance Worksheet (Ch. 14)
- (Instructions) (195 KB, 2 pages) Feb 10, 2009
- (Worksheet) (616 KB, 2 pages) Feb 10, 2009

Appendix 17: Congenital Rubella Syndrome Case Report (Ch. 15) (72 KB, 2 pages) Feb 27, 2009

Appendix 18: Tetanus Surveillance Worksheet (Ch. 16)
- (Instructions) (209 KB, 2 pages) Mar 18, 2009
- (Worksheet) (76 KB, 2 pages) Mar 18, 2009

Appendix 19: Varicella Death Investigation Worksheet (Ch. 17)
- (Instructions) (263 KB, 2 pages) Feb 23, 2009
- (Worksheet) (206 KB, 4 pages) Feb 23, 2009


Appendix 20: Varicella Outbreak Reporting & Surveillance Worksheets (Ch. 17)
- (Reporting Worksheet)
- (Surveillance Worksheet)

Appendix 21: Updated Guidelines for Evaluating Public Health Surveillance Systems (Ch. 18) (90 KB, 1 page) Jan 20, 2009

Appendix 22: VAERS Form (Ch. 21) (70 KB, 1 page) Jan 20, 2009

Appendix 23: CDC Specimen Submission Form (Ch. 22) (393 KB, 1 page) Jan 8, 2009

Appendix 24: Interstate Shipment of Etiologic Agents / Packaging and Shipping of Biomedical Material (Ch. 22) (532 KB, 4 pages) Feb 10, 2009

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Vaccines: Pubs/SurvManual/main page