domingo, 4 de abril de 2010
Autism and Family History by Genomics and Health
Genomics and Health
Autism and Family History
Autism is one of a group of disorders known as autism spectrum disorders (ASDs). ASDs include autistic disorder, pervasive developmental disorder – not otherwise specified (PDD-NOS, including atypical autism), and Asperger syndrome. These conditions all have some of the same symptoms, but they differ in terms of when the symptoms start, how severe they are, and the exact nature of the symptoms.
People at risk
ASDs occur in all racial, ethnic, and socioeconomic groups and are four times more likely to occur in boys than in girls. CDC’s Autism and Developmental Disabilities Monitoring Network released data in 2009, indicating that about one in 110 eight-year old children in multiple areas of the United States have ASDs.
http://www.cdc.gov/ncbddd/autism/addm.html
Genetics and family history
For most people with ASDs, the cause is not known. Scientists believe that both genes and the environment play a role in ASDs. Family studies have provided evidence for a genetic contribution to autism. Among identical twins, if one child has autism, the other will be affected about 60-96% of the time. The risk decreases to about 0-24% for non-identical twins. In addition, parents who have a child with ASD have a 2%-8% chance of having a second child who is also affected.
To read more about other suspected causes of ASDs, please visit the Autism Spectrum Disorders Overview web page.
http://www.cdc.gov/ncbddd/autism/index.html
Activities on ASDs
CDC conducts and funds research studies and monitoring activities to better understand and track ASDs in the United States. These research studies examine a number of potential risk factors for ASDs, such as infection and immune function, and genes that are related to these factors. CDC also conducts educational campaigns with healthcare providers and the public to help detect symptoms of ASDs early. To read more about these activities, please visit the CDC Activities web page.
The U.S. National Institutes of Health and other agencies help to support the Autism Genome Project Consortium, the largest search for autism-related genes to date. The consortium is pursuing studies to identify specific genes and gene variants that contribute to susceptibility to autism.
http://www.nimh.nih.gov/science-news/2007/largest-ever-search-for-autism-genes-reveals-new-clues.shtml
Links
General Information on Autism
Autism Information Center, CDC
http://www.cdc.gov/ncbddd/autism/index.html
Autism Research, CDC
http://www.cdc.gov/ncbddd/autism/research.html
CDC Campaign: Learn the Signs. Act Early
http://www.cdc.gov/ncbddd/actearly/index.html
Autism Spectrum Disorders, National Institute of Mental Health, NIH
http://www.nimh.nih.gov/health/topics/autism-spectrum-disorders-pervasive-developmental-disorders/index.shtml
Autism Society of America
http://www.autism-society.org/site/PageServer
Autism Speaks
http://www.autismspeaks.org/index.php
Specific Information on Autism and Genomics
Autism Genome Project Consortium
Autism Speaks: The Autism Genome Project
http://www.autismspeaks.org/press/agp_results.php
Family Health History
National Office of Public Health Genomics
http://www.cdc.gov/genomics/famhistory/index.htm
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